Search the complete CPT database. Access official guidelines, notes, modifiers, and documentation requirements instantly.
Browse the official clinical code repository for active CPT procedure classifications. Up to 50 codes are displayed per page.
| Code | Category / Specialty | Description |
|---|---|---|
| 0480T |
Procedures
General
|
Fractional ablative laser fenestration of burn and traumatic scars for functional improvement; each additional 100 cm2, or each additional 1% of body surface area of infants and children, or part thereof (List separately in addition to code for primary procedure)
|
| 0480U |
Procedures
General
|
Infectious disease (bacteria, viruses, fungi, and parasites), cerebrospinal fluid (CSF), metagenomic next-generation sequencing (DNA and RNA), bioinformatic analysis, with positive pathogen identification
|
| 0481T |
Procedures
General
|
Injection(s), autologous white blood cell concentrate (autologous protein solution), any site, including image guidance, harvesting and preparation, when performed
|
| 0481U |
Procedures
General
|
IDH1 (isocitrate dehydrogenase 1 [NADP+]), IDH2 (isocitrate dehydrogenase 2 [NADP+]), and TERT (telomerase reverse transcriptase) promoter (eg, central nervous system [CNS] tumors), next-generation sequencing (single-nucleotide variants [SNV], deletions, and insertions)
|
| 0482T |
Procedures
General
|
Absolute quantitation of myocardial blood flow, positron emission tomography (PET), rest and stress (List separately in addition to code for primary procedure)
|
| 0482U |
Procedures
General
|
Obstetrics (preeclampsia), biochemical assay of soluble fms-like tyrosine kinase 1 (sFlt-1) and placental growth factor (PlGF), serum, ratio reported for sFlt-1/PlGF, with risk of progression for preeclampsia with severe features within 2 weeks
|
| 0483T |
Procedures
General
|
Transcatheter mitral valve implantation/replacement (TMVI) with prosthetic valve; percutaneous approach, including transseptal puncture, when performed
|
| 0483U |
Procedures
General
|
Infectious disease (Neisseria gonorrhoeae), sensitivity, ciprofloxacin resistance (gyrA S91F point mutation), oral, rectal, or vaginal swab, algorithm reported as probability of fluoroquinolone resistance
|
| 0484T |
Procedures
General
|
Transcatheter mitral valve implantation/replacement (TMVI) with prosthetic valve; transthoracic exposure (eg, thoracotomy, transapical)
|
| 0484U |
Procedures
General
|
Infectious disease (Mycoplasma genitalium), macrolide sensitivity (23S rRNA point mutation), oral, rectal, or vaginal swab, algorithm reported as probability of macrolide resistance
|
| 0485T |
Procedures
General
|
Optical coherence tomography (OCT) of middle ear, with interpretation and report; unilateral
|
| 0485U |
Procedures
General
|
Oncology (solid tumor), cell-free DNA and RNA by next-generation sequencing, interpretative report for germline mutations, clonal hematopoiesis of indeterminate potential, and tumor-derived single-nucleotide variants, small insertions/deletions, copy number alterations, fusions, microsatellite instability, and tumor mutational burden
|
| 0486T |
Procedures
General
|
Optical coherence tomography (OCT) of middle ear, with interpretation and report; bilateral
|
| 0486U |
Procedures
General
|
Oncology (pan-solid tumor), next-generation sequencing analysis of tumor methylation markers present in cell-free circulating tumor DNA, algorithm reported as quantitative measurement of methylation as a correlate of tumor fraction
|
| 0487T |
Procedures
General
|
Biomechanical mapping, transvaginal, with report
|
| 0487U |
Procedures
General
|
Oncology (solid tumor), cell-free circulating DNA, targeted genomic sequence analysis panel of 84 genes, interrogation for sequence variants, aneuploidy-corrected gene copy number amplifications and losses, gene rearrangements, and microsatellite instability
|
| 0488T |
Procedures
General
|
Preventive behavior change, online/electronic structured intensive program for prevention of diabetes using a standardized diabetes prevention program curriculum, provided to an individual, per 30 days
|
| 0488U |
Procedures
General
|
Obstetrics (fetal antigen noninvasive prenatal test), cell-free DNA sequence analysis for detection of fetal presence or absence of 1 or more of the Rh, C, c, D, E, Duffy (Fya), or Kell (K) antigen in alloimmunized pregnancies, reported as selected antigen(s) detected or not detected
|
| 0489T |
Procedures
General
|
Autologous adipose-derived regenerative cell therapy for scleroderma in the hands; adipose tissue harvesting, isolation and preparation of harvested cells including incubation with cell dissociation enzymes, removal of non-viable cells and debris, determination of concentration and dilution of regenerative cells
|
| 0489U |
Procedures
General
|
Obstetrics (single-gene noninvasive prenatal test), cell-free DNA sequence analysis of 1 or more targets (eg, CFTR, SMN1, HBB, HBA1, HBA2) to identify paternally inherited pathogenic variants, and relative mutation-dosage analysis based on molecular counts to determine fetal inheritance of maternal mutation, algorithm reported as a fetal risk score for the condition (eg, cystic fibrosis, spinal muscular atrophy, beta hemoglobinopathies [including sickle cell disease], alpha thalassemia)
|
| 0490T |
Procedures
General
|
Autologous adipose-derived regenerative cell therapy for scleroderma in the hands; multiple injections in one or both hands
|
| 0490U |
Procedures
General
|
Oncology (cutaneous or uveal melanoma), circulating tumor cell selection, morphological characterization and enumeration based on differential CD146, high molecular-weight melanoma-associated antigen, CD34 and CD45 protein biomarkers, peripheral blood
|
| 0491T |
Procedures
General
|
Ablative laser treatment, non-contact, full field and fractional ablation, open wound, per day, total treatment surface area; first 20 sq cm or less
|
| 0491U |
Procedures
General
|
Oncology (solid tumor), circulating tumor cell selection, morphological characterization and enumeration based on differential epithelial cell adhesion molecule (EpCAM), cytokeratins 8, 18, and 19, CD45 protein biomarkers, and quantification of estrogen receptor (ER) protein biomarker-expressing cells, peripheral blood
|
| 0492T |
Procedures
General
|
Ablative laser treatment, non-contact, full field and fractional ablation, open wound, per day, total treatment surface area; each additional 20 sq cm, or part thereof (List separately in addition to code for primary procedure)
|
| 0492U |
Procedures
General
|
Oncology (solid tumor), circulating tumor cell selection, morphological characterization and enumeration based on differential epithelial cell adhesion molecule (EpCAM), cytokeratins 8, 18, and 19, CD45 protein biomarkers, and quantification of PD-L1 protein biomarker-expressing cells, peripheral blood
|
| 0493T |
Procedures
General
|
Contact near-infrared spectroscopy studies of lower extremity wounds (eg, for oxyhemoglobin measurement)
|
| 0493U |
Procedures
General
|
Transplantation medicine, quantification of donor-derived cell-free DNA (cfDNA) using next-generation sequencing, plasma, reported as percentage of donor-derived cell-free DNA
|
| 0494T |
Procedures
General
|
Surgical preparation and cannulation of marginal (extended) cadaver donor lung(s) to ex vivo organ perfusion system, including decannulation, separation from the perfusion system, and cold preservation of the allograft prior to implantation, when performed
|
| 0494U |
Procedures
General
|
Red blood cell antigen (fetal RhD gene analysis), next-generation sequencing of circulating cell-free DNA (cfDNA) of blood in pregnant individuals known to be RhD negative, reported as positive or negative
|
| 0495T |
Procedures
General
|
Initiation and monitoring marginal (extended) cadaver donor lung(s) organ perfusion system by physician or qualified health care professional, including physiological and laboratory assessment (eg, pulmonary artery flow, pulmonary artery pressure, left atrial pressure, pulmonary vascular resistance, mean/peak and plateau airway pressure, dynamic compliance and perfusate gas analysis), including bronchoscopy and X ray when performed; first two hours in sterile field
|
| 0495U |
Procedures
General
|
Oncology (prostate), analysis of circulating plasma proteins (tPSA, fPSA, KLK2, PSP94, and GDF15), germline polygenic risk score (60 variants), clinical information (age, family history of prostate cancer, prior negative prostate biopsy), algorithm reported as risk of likelihood of detecting clinically significant prostate cancer
|
| 0496T |
Procedures
General
|
Initiation and monitoring marginal (extended) cadaver donor lung(s) organ perfusion system by physician or qualified health care professional, including physiological and laboratory assessment (eg, pulmonary artery flow, pulmonary artery pressure, left atrial pressure, pulmonary vascular resistance, mean/peak and plateau airway pressure, dynamic compliance and perfusate gas analysis), including bronchoscopy and X ray when performed; each additional hour (List separately in addition to code for primary procedure)
|
| 0496U |
Procedures
General
|
Oncology (colorectal), cell-free DNA, 8 genes for mutations, 7 genes for methylation by real-time RT-PCR, and 4 proteins by enzyme-linked immunosorbent assay, blood, reported positive or negative for colorectal cancer or advanced adenoma risk
|
| 0497T |
Procedures
General
|
External patient-activated, physician- or other qualified health care professional-prescribed, electrocardiographic rhythm derived event recorder without 24 hour attended monitoring; in-office connection
|
| 0497U |
Procedures
General
|
Oncology (prostate), mRNA gene-expression profiling by real-time RT-PCR of 6 genes (FOXM1, MCM3, MTUS1, TTC21B, ALAS1, and PPP2CA), utilizing formalin-fixed paraffin-embedded (FFPE) tissue, algorithm reported as a risk score for prostate cancer
|
| 0498T |
Procedures
General
|
External patient-activated, physician- or other qualified health care professional-prescribed, electrocardiographic rhythm derived event recording without 24 hour attended monitoring; review and interpretation by a physician or other qualified health care professional per 30 days with at least one patient-generated triggered event
|
| 0498U |
Procedures
General
|
Oncology (colorectal), next-generation sequencing for mutation detection in 43 genes and methylation pattern in 45 genes, blood, and formalin-fixed paraffin-embedded (FFPE) tissue, report of variants and methylation pattern with interpretation
|
| 0499T |
Procedures
General
|
Cystourethroscopy, with mechanical dilation and urethral therapeutic drug delivery for urethral stricture or stenosis, including fluoroscopy, when performed
|
| 0499U |
Procedures
General
|
Oncology (colorectal and lung), DNA from formalin-fixed paraffin-embedded (FFPE) tissue, next-generation sequencing of 8 genes (NRAS, EGFR, CTNNB1, PIK3CA, APC, BRAF, KRAS, and TP53), mutation detection
|
| 0500F |
Procedures
General
|
Initial prenatal care visit (report at first prenatal encounter with health care professional providing obstetrical care. Report also date of visit and, in a separate field, the date of the last menstrual period [LMP]) (Prenatal)
|
| 0500T |
Procedures
General
|
Infectious agent detection by nucleic acid (DNA or RNA), human papillomavirus (HPV) for five or more separately reported high-risk HPV types (eg, 16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59, 68) (ie, genotyping)
|
| 0500U |
Procedures
General
|
Autoinflammatory disease (VEXAS syndrome), DNA, UBA1 gene mutations, targeted variant analysis (M41T, M41V, M41L, c.118-2A>C, c.118-1G>C, c.118-9_118-2del, S56F, S621C)
|
| 0501F |
Procedures
General
|
Prenatal flow sheet documented in medical record by first prenatal visit (documentation includes at minimum blood pressure, weight, urine protein, uterine size, fetal heart tones, and estimated date of delivery). Report also: date of visit and, in a separate field, the date of the last menstrual period [LMP] (Note: If reporting 0501F Prenatal flow sheet, it is not necessary to report 0500F Initial prenatal care visit) (Prenatal)
|
| 0501T |
Procedures
General
|
Noninvasive estimated coronary fractional flow reserve (FFR) derived from coronary computed tomography angiography data using computation fluid dynamics physiologic simulation software analysis of functional data to assess the severity of coronary artery disease; data preparation and transmission, analysis of fluid dynamics and simulated maximal coronary hyperemia, generation of estimated FFR model, with anatomical data review in comparison with estimated FFR model to reconcile discordant data, interpretation and report
|
| 0501U |
Procedures
General
|
Oncology (colorectal), blood, quantitative measurement of cell-free DNA (cfDNA)
|
| 0502F |
Procedures
General
|
Subsequent prenatal care visit (Prenatal) [Excludes: patients who are seen for a condition unrelated to pregnancy or prenatal care (eg, an upper respiratory infection; patients seen for consultation only, not for continuing care)]
|
| 0502T |
Procedures
General
|
Noninvasive estimated coronary fractional flow reserve (FFR) derived from coronary computed tomography angiography data using computation fluid dynamics physiologic simulation software analysis of functional data to assess the severity of coronary artery disease; data preparation and transmission
|
| 0502U |
Procedures
General
|
Human papillomavirus (HPV), E6/E7 markers for high-risk types (16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59, 66, and 68), cervical cells, branched-chain capture hybridization, reported as negative or positive for high risk for HPV
|
| 0503F |
Procedures
General
|
Postpartum care visit (Prenatal)
|
The Current Procedural Terminology (CPT®) code set, maintained and copyrighted by the American Medical Association (AMA), is the universal language of medicine in the United States outpatient setting. It is utilized to report medical, surgical, and diagnostic procedures and services to entities such as physicians, health insurance companies, and accreditation organizations. For the Certified Professional Coder (CPC), mastering the CPT manual is the cornerstone of professional fee (ProFee) and ambulatory surgery center (ASC) coding.
Unlike ICD-10-CM which describes the "why" (the diagnosis), CPT describes the "what" (the service or procedure performed). Translating a complex operative report or an Evaluation and Management (E/M) encounter into a 5-digit CPT code requires a profound understanding of medical terminology, anatomy, and the labyrinth of AMA guidelines. A single coding error can result in massive revenue leakage, compliance violations, or severe audit penalties.
Never code directly from the alphabetic index. The true power of the CPC lies in reading the parenthetical notes situated directly beneath the CPT codes in the tabular section. These notes dictate bundling rules, direct the coder to the correct alternative codes, and provide strict instructions on when a modifier is necessary. Ignoring a parenthetical note is a guaranteed path to a claim denial.
The CPT code set is divided into three distinct categories, each serving a unique purpose in the healthcare ecosystem.
These are the core, 5-digit numeric codes that make up the vast majority of the CPT manual. They represent procedures and services that are widely performed by many healthcare professionals in clinical practice and are approved by the FDA. Category I is divided into six main sections:
These are supplemental tracking codes used for performance measurement and quality tracking. They are alphanumeric (e.g., 3008F - Body Mass Index documented). While Category II codes are generally optional and do not carry a relative value unit (RVU) for direct reimbursement, they are highly critical in value-based purchasing agreements, MIPS (Merit-based Incentive Payment System), and MACRA reporting to secure quality bonuses.
These are temporary alphanumeric codes (ending in "T") utilized for emerging technologies, services, and procedures (e.g., 0101T - Extracorporeal shock wave involving musculoskeletal system). They allow researchers and the AMA to track the utilization of new technologies before they are granted Category I status. If a Category III code exists for a specific procedure, it must be utilized instead of an "unlisted" Category I code.
Historically, E/M coding was the most heavily audited and contentious area of medical coding, governed by the archaic 1995 and 1997 CMS Documentation Guidelines. These old guidelines required physicians to "bullet count" physical exam elements and history of present illness (HPI) components, leading to massive documentation bloat ("note bloat") in Electronic Health Records.
The AMA and CMS radically overhauled E/M coding (effective 2021 for outpatient/office, and 2023 for inpatient/facility). Today, the selection of an E/M level is based strictly on one of two criteria:
Surgical coding is governed by the concept of the Global Surgical Package. When a payer reimburses a surgical CPT code, the payment covers not just the intraoperative procedure, but also the local/topical anesthesia, normal uncomplicated follow-up care, and typical preoperative encounters.
One of the primary directives of a CPC is to prevent Unbundling. Unbundling occurs when a coder reports multiple CPT codes for components that are inherently part of a single, major procedure. To prevent this, coders rely on the National Correct Coding Initiative (NCCI) Edits. These edits dictate which codes cannot be billed together. For example, you cannot bill an exploratory laparotomy alongside an open appendectomy, as the surgical approach is bundled into the definitive procedure.
Modifiers are two-digit codes appended to a CPT code to indicate that a service or procedure has been altered by some specific circumstance but not changed in its definition. Applying the correct modifier is the ultimate test of a coder's compliance knowledge. Incorrect modifier usage is the leading cause of Office of Inspector General (OIG) audits.
CPT codes are intrinsically tied to physician compensation via the Medicare Physician Fee Schedule (MPFS). Every Category I CPT code is assigned a Relative Value Unit (RVU), which quantifies the resources required to perform the service. The total RVU is calculated by adding three components:
The Total RVU is then multiplied by a geographic practice cost index (GPCI) and the annual Medicare Conversion Factor to calculate the exact dollar amount of reimbursement.
The Certified Professional Coder is the final line of defense in the revenue cycle. A physician may perform an incredible, life-saving surgery, but if the CPC fails to correctly sequence the CPT codes, apply the correct NCCI bypass modifiers, or link the procedures to the highest-specificity ICD-10-CM diagnosis codes to prove Medical Necessity, the claim will be denied.
Beyond abstracting codes from documentation, modern CPCs act as clinical educators. They regularly audit provider documentation to ensure compliance with AMA guidelines, train physicians on the nuances of the 2021/2023 E/M updates, and query providers when an operative report lacks the critical details required to assign a complex surgical code.
The CPT code set is a dynamic, continuously evolving language that adapts to the cutting edge of medical science. New technologies, novel surgical techniques, and telemedicine expansions require the AMA to update the manual annually every January 1st.
For the professional medical coder, fluency in CPT is the key to unlocking the financial viability of a healthcare organization. It demands rigorous analytical skills, an unwavering commitment to ethical compliance, and a deep respect for the clinical realities of patient care. Whether you are coding a simple office visit or a multi-stage cardiothoracic surgery, your mastery of CPT ensures that the physician's work is accurately recognized, fully reimbursed, and protected from retrospective audits.
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Looking up medical codes can often be a frustrating and time-consuming experience, especially when relying on slow, clunky platforms or physical manuals that quickly become outdated. Our dedicated CPT search directory elegantly bridges that gap. By utilizing our highly optimized, state-of-the-art database, you can effortlessly find CPT code descriptions by simply typing a keyword, a specific diagnosis or procedure, an anatomical site, or the exact alphanumeric code itself. The results are rendered in real-time as you type, allowing you to completely bypass cumbersome PDF manuals and heavy physical coding books, streamlining your daily workflow.
To perform an accurate CPT lookup, navigate to the intuitive search bar located at the top of this page. If you have a specific clinical term or abstract concept in mind, simply type the term into the search field. Our intelligent, NLP-driven algorithm will instantly scan the entire official database to populate a comprehensive list of matching CPT codes and descriptions. Conversely, if you already possess the specific code and simply need to verify its validity or read the full tabular guidelines, you can type the identifier directly into the bar to instantly verify its official long-form description.
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