Official Coding Guidelines

CPT Dictionary

Search the complete CPT database. Access official guidelines, notes, modifiers, and documentation requirements instantly.

CPT Code Reference Directory

Browse the official clinical code repository for active CPT procedure classifications. Up to 50 codes are displayed per page.

Code Category / Specialty Description
0566U
Procedures
General
Oncology (lung), qPCR-based analysis of 13 differentially methylated regions (CCDC181, HOXA7, LRRC8A, MARCHF11, MIR129-2, NCOR2, PANTR1, PRKCB, SLC9A3, TBR1_2, TRAP1, VWC2, ZNF781), pleural fluid, algorithm reported as a qualitative result
0567T
Procedures
General
Permanent fallopian tube occlusion with degradable biopolymer implant, transcervical approach, including transvaginal ultrasound
0567U
Procedures
General
Rare diseases (constitutional/heritable disorders), whole-genome sequence analysis combination of short and long reads, for single-nucleotide variants, insertions/deletions and characterized intronic variants, copy-number variants, duplications/deletions, mobile element insertions, runs of homozygosity, aneuploidy, and inversions, mitochondrial DNA sequence and deletions, short tandem repeat genes, methylation status of selected regions, blood, saliva, amniocentesis, chorionic villus sample or tissue, identification and categorization of genetic variants
0568T
Procedures
General
Introduction of mixture of saline and air for sonosalpingography to confirm occlusion of fallopian tubes, transcervical approach, including transvaginal ultrasound and pelvic ultrasound
0568U
Procedures
General
Neurology (dementia), beta amyloid (AB40, AB42, AB42/40 ratio), tau-protein phosphorylated at residue (eg, pTau217), neurofilament light chain (NfL), and glial fibrillary acidic protein (GFAP), by ultra-high sensitivity molecule array detection, plasma, algorithm reported as positive, intermediate, or negative for Alzheimer pathology
0569T
Procedures
General
Transcatheter tricuspid valve repair, percutaneous approach; initial prosthesis
0569U
Procedures
General
Oncology (solid tumor), next-generation sequencing analysis of tumor methylation markers (>20000 differentially methylated regions) present in cell-free circulating tumor DNA (ctDNA), whole blood, algorithm reported as presence or absence of ctDNA with tumor fraction, if appropriate
0570T
Procedures
General
Transcatheter tricuspid valve repair, percutaneous approach; each additional prosthesis during same session (List separately in addition to code for primary procedure)
0570U
Procedures
General
Neurology (traumatic brain injury), analysis of glial fibrillary acidic protein (GFAP) and ubiquitin carboxyl-terminal hydrolase L1 (UCH-L1), immunoassay, whole blood or plasma, individual components reported with the overall result of elevated or non-elevated based on threshold comparison
0571T
Procedures
General
Insertion or replacement of implantable cardioverter-defibrillator system with substernal electrode(s), including all imaging guidance and electrophysiological evaluation (includes defibrillation threshold evaluation, induction of arrhythmia, evaluation of sensing for arrhythmia termination, and programming or reprogramming of sensing or therapeutic parameters), when performed
0571U
Procedures
General
Oncology (solid tumor), DNA (80 genes) and RNA (10 genes), by next-generation sequencing, plasma, including single-nucleotide variants, insertions/deletions, copy-number alterations, microsatellite instability, and fusions, reported as clinically actionable variants
0572T
Procedures
General
Insertion of substernal implantable defibrillator electrode
0572U
Procedures
General
Oncology (prostate), high-throughput telomere length quantification by FISH, whole blood, diagnostic algorithm reported as risk of prostate cancer
0573T
Procedures
General
Removal of substernal implantable defibrillator electrode
0573U
Procedures
General
Oncology (pancreas), 3 biomarkers (glucose, carcinoembryonic antigen, and gastricsin), pancreatic cyst lesion fluid, algorithm reported as categorical mucinous or non-mucinous
0574T
Procedures
General
Repositioning of previously implanted substernal implantable defibrillator-pacing electrode
0574U
Procedures
General
Mycobacterium tuberculosis, culture filtrate protein-10-kDa (CFP-10), serum or plasma, liquid chromatography mass spectrometry (LC-MS)
0575F
Procedures
General
HIV RNA control plan of care, documented (HIV)
0575T
Procedures
General
Programming device evaluation (in person) of implantable cardioverter-defibrillator system with substernal electrode, with iterative adjustment of the implantable device to test the function of the device and select optimal permanent programmed values with analysis, review and report by a physician or other qualified health care professional
0575U
Procedures
General
Transplantation medicine (liver allograft rejection), miRNA gene expression profiling by RT-PCR of 4 genes (miR-122, miR-885, miR-23a housekeeping, spike-in control), serum, algorithm reported as risk of liver allograft rejection
0576T
Procedures
General
Interrogation device evaluation (in person) of implantable cardioverter-defibrillator system with substernal electrode, with analysis, review and report by a physician or other qualified health care professional, includes connection, recording and disconnection per patient encounter
0576U
Procedures
General
Transplantation medicine (liver allograft rejection), quantitative donor-derived cell-free DNA (cfDNA) by whole genome next-generation sequencing, plasma and mRNA gene expression profiling by multiplex real-time PCR of 56 genes, whole blood, combined algorithm reported as a rejection risk score
0577T
Procedures
General
Electrophysiological evaluation of implantable cardioverter-defibrillator system with substernal electrode (includes defibrillation threshold evaluation, induction of arrhythmia, evaluation of sensing for arrhythmia termination, and programming or reprogramming of sensing or therapeutic parameters)
0577U
Procedures
General
Oncology (ovarian), serum, analysis of 39 glycoproteins by liquid chromatography with tandem mass spectrometry (LC-MS/MS) in multiple reaction monitoring mode, reported as likelihood of malignancy
0578T
Procedures
General
Interrogation device evaluation(s) (remote), up to 90 days, substernal lead implantable cardioverter-defibrillator system with interim analysis, review(s) and report(s) by a physician or other qualified health care professional
0578U
Procedures
General
Oncology (cutaneous melanoma), RNA, gene expression profiling by real-time qPCR of 10 genes (8 content and 2 housekeeping), utilizing formalin-fixed paraffin-embedded (FFPE) tissue, algorithm reports a binary result, either low-risk or high-risk for sentinel lymph node metastasis and recurrence
0579T
Procedures
General
Interrogation device evaluation(s) (remote), up to 90 days, substernal lead implantable cardioverter-defibrillator system, remote data acquisition(s), receipt of transmissions and technician review, technical support and distribution of results
0579U
Procedures
General
Nephrology (diabetic chronic kidney disease), enzyme-linked immunosorbent assay (ELISA) of apolipoprotein A4 (APOA4), CD5 antigen-like (CD5L) combined with estimated glomerular filtration rate (GFR), age, plasma, algorithm reported as a risk score for kidney function decline
0580F
Procedures
General
Multidisciplinary care plan developed or updated (ALS)
0580T
Procedures
General
Removal of substernal implantable defibrillator pulse generator only
0580U
Procedures
General
Borrelia burgdorferi, antibody detection of 24 recombinant protein groups, by immunoassay, IgG
0581F
Procedures
General
Patient transferred directly from anesthetizing location to critical care unit (Peri2)
0581T
Procedures
General
Ablation, malignant breast tumor(s), percutaneous, cryotherapy, including imaging guidance when performed, unilateral
0581U
Procedures
General
Transplantation medicine, antibody to non-human leukocyte antigens (non-HLA), blood specimen, flow cytometry, single-antigen bead technology, 39 targets, individual positive antibodies reported
0582F
Procedures
General
Patient not transferred directly from anesthetizing location to critical care unit (Peri2)
0582T
Procedures
General
Transurethral ablation of malignant prostate tissue by high-energy water vapor thermotherapy, including intraoperative imaging and needle guidance
0582U
Procedures
General
Rare diseases (constitutional disease/hereditary disorders), rapid whole genome DNA sequencing for single-nucleotide variants, insertions/deletions, copy number variations, blood, saliva, tissue sample, variants reported
0583F
Procedures
General
Transfer of care checklist used (Peri2)
0583T
Procedures
General
Tympanostomy (requiring insertion of ventilating tube), using an automated tube delivery system, iontophoresis local anesthesia
0583U
Procedures
General
Rare diseases (constitutional disease/hereditary disorders), rapid whole genome comparator DNA sequencing for single-nucleotide variants, insertions/deletions, copy number variations, blood, saliva, tissue sample, variants reported with proband results (List separately in addition to code for primary procedure)
0584F
Procedures
General
Transfer of care checklist not used (Peri2)
0584T
Procedures
General
Islet cell transplant, includes portal vein catheterization and infusion, including all imaging, including guidance, and radiological supervision and interpretation, when performed; percutaneous
0584U
Procedures
General
Neurology (prion disease), cerebrospinal fluid, detection of prion protein by quaking-induced conformational conversion, qualitative
0585T
Procedures
General
Islet cell transplant, includes portal vein catheterization and infusion, including all imaging, including guidance, and radiological supervision and interpretation, when performed; laparoscopic
0585U
Procedures
General
Targeted genomic sequence analysis panel, solid organ neoplasm, circulating cell-free DNA (cfDNA) analysis from plasma of 521 genes, interrogation for sequence variants, gene copy number amplifications, gene rearrangements, and microsatellite instability, report shows identified mutations, including variants with clinical actionability
0586T
Procedures
General
Islet cell transplant, includes portal vein catheterization and infusion, including all imaging, including guidance, and radiological supervision and interpretation, when performed; open
0586U
Procedures
General
Oncology, mRNA, gene expression profiling of 216 genes (204 targeted and 12 housekeeping genes), RNA expression analysis, formalin-fixed paraffin-embedded (FFPE) tissue, quantitative, reported as log2 ratio per gene
0587T
Procedures
General
Percutaneous implantation or replacement of integrated single device neurostimulation system including electrode array and receiver or pulse generator, including analysis, programming, and imaging guidance when performed, posterior tibial nerve
0587U
Procedures
General
Therapeutic drug monitoring, 60-150 drugs and metabolites, urine, saliva, quantitative liquid chromatography with tandem mass spectrometry (LC-MS/MS), specimen validity, and algorithmic analyses for presence or absence of drug or metabolite, risk score predicted for adverse drug effects
0588T
Procedures
General
Revision or removal of integrated single device neurostimulation system including electrode array and receiver or pulse generator, including analysis, programming, and imaging guidance when performed, posterior tibial nerve
Showing page 26 of 253 (Total: 12623 codes)

The Ultimate Guide to CPT Coding: Navigating the Outpatient Revenue Cycle

The Current Procedural Terminology (CPT®) code set, maintained and copyrighted by the American Medical Association (AMA), is the universal language of medicine in the United States outpatient setting. It is utilized to report medical, surgical, and diagnostic procedures and services to entities such as physicians, health insurance companies, and accreditation organizations. For the Certified Professional Coder (CPC), mastering the CPT manual is the cornerstone of professional fee (ProFee) and ambulatory surgery center (ASC) coding.

Unlike ICD-10-CM which describes the "why" (the diagnosis), CPT describes the "what" (the service or procedure performed). Translating a complex operative report or an Evaluation and Management (E/M) encounter into a 5-digit CPT code requires a profound understanding of medical terminology, anatomy, and the labyrinth of AMA guidelines. A single coding error can result in massive revenue leakage, compliance violations, or severe audit penalties.

CPC Coder's Note: The Importance of the Parenthetical Notes

Never code directly from the alphabetic index. The true power of the CPC lies in reading the parenthetical notes situated directly beneath the CPT codes in the tabular section. These notes dictate bundling rules, direct the coder to the correct alternative codes, and provide strict instructions on when a modifier is necessary. Ignoring a parenthetical note is a guaranteed path to a claim denial.

The Three Categories of CPT Codes

The CPT code set is divided into three distinct categories, each serving a unique purpose in the healthcare ecosystem.

Category I Codes

These are the core, 5-digit numeric codes that make up the vast majority of the CPT manual. They represent procedures and services that are widely performed by many healthcare professionals in clinical practice and are approved by the FDA. Category I is divided into six main sections:

  • Evaluation and Management (99202–99499): Cognitive services, office visits, hospital observations, and consultations.
  • Anesthesiology (00100–01999): Anesthesia services, categorized by anatomical site.
  • Surgery (10021–69990): The largest section, covering all surgical procedures organized by body system (Integumentary, Musculoskeletal, Respiratory, Cardiovascular, etc.).
  • Radiology (70010–79999): Diagnostic imaging, ultrasound, radiation oncology, and nuclear medicine.
  • Pathology and Laboratory (80047–89398): Organ or disease-oriented panels, drug testing, hematology, and surgical pathology.
  • Medicine (90281–99607): Immunizations, psychiatry, physical therapy, ophthalmology, and cardiac catheterizations.

Category II Codes

These are supplemental tracking codes used for performance measurement and quality tracking. They are alphanumeric (e.g., 3008F - Body Mass Index documented). While Category II codes are generally optional and do not carry a relative value unit (RVU) for direct reimbursement, they are highly critical in value-based purchasing agreements, MIPS (Merit-based Incentive Payment System), and MACRA reporting to secure quality bonuses.

Category III Codes

These are temporary alphanumeric codes (ending in "T") utilized for emerging technologies, services, and procedures (e.g., 0101T - Extracorporeal shock wave involving musculoskeletal system). They allow researchers and the AMA to track the utilization of new technologies before they are granted Category I status. If a Category III code exists for a specific procedure, it must be utilized instead of an "unlisted" Category I code.

Mastering Evaluation and Management (E/M)

Historically, E/M coding was the most heavily audited and contentious area of medical coding, governed by the archaic 1995 and 1997 CMS Documentation Guidelines. These old guidelines required physicians to "bullet count" physical exam elements and history of present illness (HPI) components, leading to massive documentation bloat ("note bloat") in Electronic Health Records.

The AMA and CMS radically overhauled E/M coding (effective 2021 for outpatient/office, and 2023 for inpatient/facility). Today, the selection of an E/M level is based strictly on one of two criteria:

  • Medical Decision Making (MDM): The cognitive effort required to treat the patient. MDM is determined by evaluating three elements: the number and complexity of problems addressed, the amount and/or complexity of data reviewed/analyzed, and the risk of complications and/or morbidity or mortality of patient management.
  • Total Time: If time is the determining factor, it now includes both face-to-face and non-face-to-face time spent by the physician on the day of the encounter (e.g., reviewing records before the patient arrives, charting after the patient leaves).

The Surgery Section: Global Periods and Unbundling

Surgical coding is governed by the concept of the Global Surgical Package. When a payer reimburses a surgical CPT code, the payment covers not just the intraoperative procedure, but also the local/topical anesthesia, normal uncomplicated follow-up care, and typical preoperative encounters.

  • 0-Day Global: Minor procedures (e.g., endoscopies). No post-operative days are included.
  • 10-Day Global: Minor procedures with a 10-day post-operative period included (e.g., simple laceration repair).
  • 90-Day Global: Major surgeries (e.g., joint replacements, open heart surgery). Includes 1 day pre-operative and 90 days post-operative care.

One of the primary directives of a CPC is to prevent Unbundling. Unbundling occurs when a coder reports multiple CPT codes for components that are inherently part of a single, major procedure. To prevent this, coders rely on the National Correct Coding Initiative (NCCI) Edits. These edits dictate which codes cannot be billed together. For example, you cannot bill an exploratory laparotomy alongside an open appendectomy, as the surgical approach is bundled into the definitive procedure.

The Power of CPT Modifiers

Modifiers are two-digit codes appended to a CPT code to indicate that a service or procedure has been altered by some specific circumstance but not changed in its definition. Applying the correct modifier is the ultimate test of a coder's compliance knowledge. Incorrect modifier usage is the leading cause of Office of Inspector General (OIG) audits.

Critical Modifiers for the CPC:

  • Modifier 25: Significant, Separately Identifiable Evaluation and Management Service by the Same Physician on the Same Day of the Procedure or Other Service. (e.g., A patient comes in for a scheduled knee injection, but also complains of a new, acute asthma attack. The asthma evaluation is billed with a -25 modifier). This is the most heavily audited modifier in existence.
  • Modifier 59 / X-Modifiers (XE, XP, XS, XU): Distinct Procedural Service. Used to bypass an NCCI edit when a procedure is performed on a separate anatomical site, through a separate incision, or during a separate session on the same day.
  • Modifier 24: Unrelated Evaluation and Management Service by the Same Physician During a Postoperative Period. Used when a surgeon sees a patient for a completely new issue during the 90-day global period of a previous surgery.
  • Modifier 57: Decision for Surgery. Appended to an E/M code when the visit results in the initial decision to perform a major surgical procedure (90-day global) on that day or the next.
  • Modifier 52: Reduced Services. Used when a procedure is partially reduced or eliminated at the physician's discretion.

Relative Value Units (RVUs) and the Physician Fee Schedule

CPT codes are intrinsically tied to physician compensation via the Medicare Physician Fee Schedule (MPFS). Every Category I CPT code is assigned a Relative Value Unit (RVU), which quantifies the resources required to perform the service. The total RVU is calculated by adding three components:

  • Work RVU (wRVU): The physician's time, mental effort, technical skill, and psychological stress. (This is how most physicians calculate their productivity bonuses).
  • Practice Expense RVU (peRVU): The overhead costs of the practice (staff salaries, rent, medical supplies). This varies based on whether the procedure is performed in a facility (hospital) or non-facility (private office).
  • Malpractice RVU (mpRVU): The cost of professional liability insurance.

The Total RVU is then multiplied by a geographic practice cost index (GPCI) and the annual Medicare Conversion Factor to calculate the exact dollar amount of reimbursement.

The Role of the CPC in the Revenue Cycle

The Certified Professional Coder is the final line of defense in the revenue cycle. A physician may perform an incredible, life-saving surgery, but if the CPC fails to correctly sequence the CPT codes, apply the correct NCCI bypass modifiers, or link the procedures to the highest-specificity ICD-10-CM diagnosis codes to prove Medical Necessity, the claim will be denied.

Beyond abstracting codes from documentation, modern CPCs act as clinical educators. They regularly audit provider documentation to ensure compliance with AMA guidelines, train physicians on the nuances of the 2021/2023 E/M updates, and query providers when an operative report lacks the critical details required to assign a complex surgical code.

Conclusion

The CPT code set is a dynamic, continuously evolving language that adapts to the cutting edge of medical science. New technologies, novel surgical techniques, and telemedicine expansions require the AMA to update the manual annually every January 1st.

For the professional medical coder, fluency in CPT is the key to unlocking the financial viability of a healthcare organization. It demands rigorous analytical skills, an unwavering commitment to ethical compliance, and a deep respect for the clinical realities of patient care. Whether you are coding a simple office visit or a multi-stage cardiothoracic surgery, your mastery of CPT ensures that the physician's work is accurately recognized, fully reimbursed, and protected from retrospective audits.

Free CPT Code Lookup & Search Tool

Welcome to the most comprehensive and lightning-fast CPT code lookup tool available online. Whether you are a dedicated health information management (HIM) professional, a certified medical coder, a specialized biller, or a clinical data analyst, our advanced search engine allows you to instantly search CPT codes and find highly accurate code descriptions in mere milliseconds. Navigating the complex world of healthcare terminology requires precision, and our platform is built to deliver exactly that.

Looking up medical codes can often be a frustrating and time-consuming experience, especially when relying on slow, clunky platforms or physical manuals that quickly become outdated. Our dedicated CPT search directory elegantly bridges that gap. By utilizing our highly optimized, state-of-the-art database, you can effortlessly find CPT code descriptions by simply typing a keyword, a specific diagnosis or procedure, an anatomical site, or the exact alphanumeric code itself. The results are rendered in real-time as you type, allowing you to completely bypass cumbersome PDF manuals and heavy physical coding books, streamlining your daily workflow.

How to Use Our CPT Search Engine for Maximum Efficiency

To perform an accurate CPT lookup, navigate to the intuitive search bar located at the top of this page. If you have a specific clinical term or abstract concept in mind, simply type the term into the search field. Our intelligent, NLP-driven algorithm will instantly scan the entire official database to populate a comprehensive list of matching CPT codes and descriptions. Conversely, if you already possess the specific code and simply need to verify its validity or read the full tabular guidelines, you can type the identifier directly into the bar to instantly verify its official long-form description.

Our platform is meticulously engineered specifically for medical coders, billers, and clinical analysts who demand both speed and unwavering accuracy. When you search for CPT codes on our website, you are guaranteed to receive the exact, official nomenclature published by the governing bodies. We provide the full tabular descriptions, ensuring that you understand the precise clinical nuances, including essential modifiers, bundling edits, and specific indicators required for clean claim submission and flawless clinical documentation.

Why Fast, Accurate Medical Code Lookup Matters in Healthcare

In the incredibly fast-paced environment of medical auditing, clinical documentation improvement (CDI), and revenue cycle management (RCM), time literally equates to money. Slow, laggy search platforms cause unnecessary friction and contribute to coder burnout. That is exactly why our free CPT lookup tool is aggressively engineered to return complex search results in under 120 milliseconds. We have heavily optimized our backend server architecture so that the moment you need to look up a CPT code, the data is delivered instantaneously. This relentless focus on performance makes our platform the premier, go-to destination for anyone in the healthcare industry asking, "How do I find a CPT code description quickly and reliably?"

We highly recommend that you bookmark this page as your daily, primary resource for all your CPT code search needs. We are deeply committed to maintaining this robust, frequently updated database as a permanent, free public utility for the global healthcare data community. Start typing your query into the search bar above to experience the absolute fastest, most reliable medical code lookup available on the internet today. Say goodbye to endless scrolling, frustrating page loads, and outdated indexes. Let our powerful, instantaneous search engine do the heavy lifting for your clinical documentation and coding operations. Whether you are aggressively searching by an exact code, a partial clinical description, or a broad medical category, our advanced tool delivers the exact CPT code information you need to ensure total compliance and financial accuracy.