Search the complete CPT database. Access official guidelines, notes, modifiers, and documentation requirements instantly.
Browse the official clinical code repository for active CPT procedure classifications. Up to 50 codes are displayed per page.
| Code | Category / Specialty | Description |
|---|---|---|
| 0404U |
Procedures
General
|
Oncology (breast), semiquantitative measurement of thymidine kinase activity by immunoassay, serum, results reported as risk of disease progression
|
| 0405T |
Procedures
General
|
Oversight of the care of an extracorporeal liver assist system patient requiring review of status, review of laboratories and other studies, and revision of orders and liver assist care plan (as appropriate), within a calendar month, 30 minutes or more of non-face-to-face time
|
| 0405U |
Procedures
General
|
Oncology (pancreatic), 59 methylation haplotype block markers, next-generation sequencing, plasma, reported as cancer signal detected or not detected
|
| 0406T |
Procedures
General
|
Nasal endoscopy, surgical, ethmoid sinus, placement of drug eluting implant;
|
| 0406U |
Procedures
General
|
Oncology (lung), flow cytometry, sputum, 5 markers (meso-tetra [4-carboxyphenyl] porphyrin [TCPP], CD206, CD66b, CD3, CD19), algorithm reported as likelihood of lung cancer
|
| 0407T |
Procedures
General
|
Nasal endoscopy, surgical, ethmoid sinus, placement of drug eluting implant; with biopsy, polypectomy or debridement
|
| 0407U |
Procedures
General
|
Nephrology (diabetic chronic kidney disease [CKD]), multiplex electrochemiluminescent immunoassay (ECLIA) of soluble tumor necrosis factor receptor 1 (sTNFR1), soluble tumor necrosis receptor 2 (sTNFR2), and kidney injury molecule 1 (KIM-1) combined with clinical data, plasma, algorithm reported as risk for progressive decline in kidney function
|
| 0408T |
Procedures
General
|
Insertion or replacement of permanent cardiac contractility modulation system, including contractility evaluation when performed, and programming of sensing and therapeutic parameters; pulse generator with transvenous electrodes
|
| 0408U |
Procedures
General
|
Infectious agent antigen detection by bulk acoustic wave biosensor immunoassay, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) (coronavirus disease [COVID-19])
|
| 0409T |
Procedures
General
|
Insertion or replacement of permanent cardiac contractility modulation system, including contractility evaluation when performed, and programming of sensing and therapeutic parameters; pulse generator only
|
| 0409U |
Procedures
General
|
Oncology (solid tumor), DNA (80 genes) and RNA (36 genes), by next-generation sequencing from plasma, including single nucleotide variants, insertions/deletions, copy number alterations, microsatellite instability, and fusions, report showing identified mutations with clinical actionability
|
| 0410T |
Procedures
General
|
Insertion or replacement of permanent cardiac contractility modulation system, including contractility evaluation when performed, and programming of sensing and therapeutic parameters; atrial electrode only
|
| 0410U |
Procedures
General
|
Oncology (pancreatic), DNA, whole genome sequencing with 5-hydroxymethylcytosine enrichment, whole blood or plasma, algorithm reported as cancer detected or not detected
|
| 0411T |
Procedures
General
|
Insertion or replacement of permanent cardiac contractility modulation system, including contractility evaluation when performed, and programming of sensing and therapeutic parameters; ventricular electrode only
|
| 0411U |
Procedures
General
|
Psychiatry (eg, depression, anxiety, attention deficit hyperactivity disorder [ADHD]), genomic analysis panel, variant analysis of 15 genes, including deletion/duplication analysis of CYP2D6
|
| 0412T |
Procedures
General
|
Removal of permanent cardiac contractility modulation system; pulse generator only
|
| 0412U |
Procedures
General
|
Beta amyloid, AB42/40 ratio, immunoprecipitation with quantitation by liquid chromatography with tandem mass spectrometry (LC-MS/MS) and qualitative ApoE isoform-specific proteotyping, plasma combined with age, algorithm reported as presence or absence of brain amyloid pathology
|
| 0413T |
Procedures
General
|
Removal of permanent cardiac contractility modulation system; transvenous electrode (atrial or ventricular)
|
| 0413U |
Procedures
General
|
Oncology (hematolymphoid neoplasm), optical genome mapping for copy number alterations, aneuploidy, and balanced/complex structural rearrangements, DNA from blood or bone marrow, report of clinically significant alterations
|
| 0414T |
Procedures
General
|
Removal and replacement of permanent cardiac contractility modulation system pulse generator only
|
| 0414U |
Procedures
General
|
Oncology (lung), augmentative algorithmic analysis of digitized whole slide imaging for 8 genes (ALK, BRAF, EGFR, ERBB2, MET, NTRK1-3, RET, ROS1), and KRAS G12C and PD-L1, if performed, formalin-fixed paraffin-embedded (FFPE) tissue, reported as positive or negative for each biomarker
|
| 0415T |
Procedures
General
|
Repositioning of previously implanted cardiac contractility modulation transvenous electrode (atrial or ventricular lead)
|
| 0415U |
Procedures
General
|
Cardiovascular disease (acute coronary syndrome [ACS]), IL-16, FAS, FASLigand, HGF, CTACK, EOTAXIN, and MCP-3 by immunoassay combined with age, sex, family history, and personal history of diabetes, blood, algorithm reported as a 5-year (deleted risk) score for ACS
|
| 0416T |
Procedures
General
|
Relocation of skin pocket for implanted cardiac contractility modulation pulse generator
|
| 0416U |
Procedures
General
|
Infectious agent detection by nucleic acid (DNA), genitourinary pathogens, identification of 20 bacterial and fungal organisms, including identification of 20 associated antibiotic-resistance genes, if performed, multiplex amplified probe technique, urine
|
| 0417T |
Procedures
General
|
Programming device evaluation (in person) with iterative adjustment of the implantable device to test the function of the device and select optimal permanent programmed values with analysis, including review and report, implantable cardiac contractility modulation system
|
| 0417U |
Procedures
General
|
Rare diseases (constitutional/heritable disorders), whole mitochondrial genome sequence with heteroplasmy detection and deletion analysis, nuclear-encoded mitochondrial gene analysis of 335 nuclear genes, including sequence changes, deletions, insertions, and copy number variants analysis, blood or saliva, identification and categorization of mitochondrial disorder-associated genetic variants
|
| 0418T |
Procedures
General
|
Interrogation device evaluation (in person) with analysis, review and report, includes connection, recording and disconnection per patient encounter, implantable cardiac contractility modulation system
|
| 0418U |
Procedures
General
|
Oncology (breast), augmentative algorithmic analysis of digitized whole slide imaging of 8 histologic and immunohistochemical features, reported as a recurrence score
|
| 0419T |
Procedures
General
|
Destruction of neurofibroma, extensive (cutaneous, dermal extending into subcutaneous); face, head and neck, greater than 50 neurofibromas
|
| 0419U |
Procedures
General
|
Neuropsychiatry (eg, depression, anxiety), genomic sequence analysis panel, variant analysis of 13 genes, saliva or buccal swab, report of each gene phenotype
|
| 0420T |
Procedures
General
|
Destruction of neurofibroma, extensive (cutaneous, dermal extending into subcutaneous); trunk and extremities, extensive, greater than 100 neurofibromas
|
| 0420U |
Procedures
General
|
Oncology (urothelial), mRNA expression profiling by real-time quantitative PCR of MDK, HOXA13, CDC2, IGFBP5, and CXCR2 in combination with droplet digital PCR (ddPCR) analysis of 6 single-nucleotide polymorphisms (SNPs) genes TERT and FGFR3, urine, algorithm reported as a risk score for urothelial carcinoma
|
| 0421T |
Procedures
General
|
Transurethral waterjet ablation of prostate, including control of post-operative bleeding, including ultrasound guidance, complete (vasectomy, meatotomy, cystourethroscopy, urethral calibration and/or dilation, and internal urethrotomy are included when performed)
|
| 0421U |
Procedures
General
|
Oncology (colorectal) screening, quantitative real-time target and signal amplification of 8 RNA markers (GAPDH, SMAD4, ACY1, AREG, CDH1, KRAS, TNFRSF10B, EGLN2) and fecal hemoglobin, algorithm reported as a positive or negative for colorectal cancer risk
|
| 0422U |
Procedures
General
|
Oncology (pan-solid tumor), analysis of DNA biomarker response to anti-cancer therapy using cell-free circulating DNA, biomarker comparison to a previous baseline pre-treatment cell-free circulating DNA analysis using next-generation sequencing, algorithm reported as a quantitative change from baseline, including specific alterations, if appropriate
|
| 0423T |
Procedures
General
|
Secretory type II phospholipase A2 (sPLA2-IIA)
|
| 0423U |
Procedures
General
|
Psychiatry (eg, depression, anxiety), genomic analysis panel, including variant analysis of 26 genes, buccal swab, report including metabolizer status and risk of drug toxicity by condition
|
| 0424T |
Procedures
General
|
Insertion or replacement of neurostimulator system for treatment of central sleep apnea; complete system (transvenous placement of right or left stimulation lead, sensing lead, implantable pulse generator)
|
| 0424U |
Procedures
General
|
Oncology (prostate), exosome-based analysis of 53 small noncoding RNAs (sncRNAs) by quantitative reverse transcription polymerase chain reaction (RT-qPCR), urine, reported as no molecular evidence, low-, moderate- or elevated-risk of prostate cancer
|
| 0425T |
Procedures
General
|
Insertion or replacement of neurostimulator system for treatment of central sleep apnea; sensing lead only
|
| 0425U |
Procedures
General
|
Genome (eg, unexplained constitutional or heritable disorder or syndrome), rapid sequence analysis, each comparator genome (eg, parents, siblings)
|
| 0426T |
Procedures
General
|
Insertion or replacement of neurostimulator system for treatment of central sleep apnea; stimulation lead only
|
| 0426U |
Procedures
General
|
Genome (eg, unexplained constitutional or heritable disorder or syndrome), ultra-rapid sequence analysis
|
| 0427T |
Procedures
General
|
Insertion or replacement of neurostimulator system for treatment of central sleep apnea; pulse generator only
|
| 0427U |
Procedures
General
|
Monocyte distribution width, whole blood (List separately in addition to code for primary procedure)
|
| 0428T |
Procedures
General
|
Removal of neurostimulator system for treatment of central sleep apnea; pulse generator only
|
| 0428U |
Procedures
General
|
Oncology (breast), targeted hybrid-capture genomic sequence analysis panel, circulating tumor DNA (ctDNA) analysis of 56 or more genes, interrogation for sequence variants, gene copy number amplifications, gene rearrangements, microsatellite instability, and tumor mutation burden
|
| 0429T |
Procedures
General
|
Removal of neurostimulator system for treatment of central sleep apnea; sensing lead only
|
| 0429U |
Procedures
General
|
Human papillomavirus (HPV), oropharyngeal swab, 14 high-risk types (ie, 16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59, 66, and 68)
|
The Current Procedural Terminology (CPT®) code set, maintained and copyrighted by the American Medical Association (AMA), is the universal language of medicine in the United States outpatient setting. It is utilized to report medical, surgical, and diagnostic procedures and services to entities such as physicians, health insurance companies, and accreditation organizations. For the Certified Professional Coder (CPC), mastering the CPT manual is the cornerstone of professional fee (ProFee) and ambulatory surgery center (ASC) coding.
Unlike ICD-10-CM which describes the "why" (the diagnosis), CPT describes the "what" (the service or procedure performed). Translating a complex operative report or an Evaluation and Management (E/M) encounter into a 5-digit CPT code requires a profound understanding of medical terminology, anatomy, and the labyrinth of AMA guidelines. A single coding error can result in massive revenue leakage, compliance violations, or severe audit penalties.
Never code directly from the alphabetic index. The true power of the CPC lies in reading the parenthetical notes situated directly beneath the CPT codes in the tabular section. These notes dictate bundling rules, direct the coder to the correct alternative codes, and provide strict instructions on when a modifier is necessary. Ignoring a parenthetical note is a guaranteed path to a claim denial.
The CPT code set is divided into three distinct categories, each serving a unique purpose in the healthcare ecosystem.
These are the core, 5-digit numeric codes that make up the vast majority of the CPT manual. They represent procedures and services that are widely performed by many healthcare professionals in clinical practice and are approved by the FDA. Category I is divided into six main sections:
These are supplemental tracking codes used for performance measurement and quality tracking. They are alphanumeric (e.g., 3008F - Body Mass Index documented). While Category II codes are generally optional and do not carry a relative value unit (RVU) for direct reimbursement, they are highly critical in value-based purchasing agreements, MIPS (Merit-based Incentive Payment System), and MACRA reporting to secure quality bonuses.
These are temporary alphanumeric codes (ending in "T") utilized for emerging technologies, services, and procedures (e.g., 0101T - Extracorporeal shock wave involving musculoskeletal system). They allow researchers and the AMA to track the utilization of new technologies before they are granted Category I status. If a Category III code exists for a specific procedure, it must be utilized instead of an "unlisted" Category I code.
Historically, E/M coding was the most heavily audited and contentious area of medical coding, governed by the archaic 1995 and 1997 CMS Documentation Guidelines. These old guidelines required physicians to "bullet count" physical exam elements and history of present illness (HPI) components, leading to massive documentation bloat ("note bloat") in Electronic Health Records.
The AMA and CMS radically overhauled E/M coding (effective 2021 for outpatient/office, and 2023 for inpatient/facility). Today, the selection of an E/M level is based strictly on one of two criteria:
Surgical coding is governed by the concept of the Global Surgical Package. When a payer reimburses a surgical CPT code, the payment covers not just the intraoperative procedure, but also the local/topical anesthesia, normal uncomplicated follow-up care, and typical preoperative encounters.
One of the primary directives of a CPC is to prevent Unbundling. Unbundling occurs when a coder reports multiple CPT codes for components that are inherently part of a single, major procedure. To prevent this, coders rely on the National Correct Coding Initiative (NCCI) Edits. These edits dictate which codes cannot be billed together. For example, you cannot bill an exploratory laparotomy alongside an open appendectomy, as the surgical approach is bundled into the definitive procedure.
Modifiers are two-digit codes appended to a CPT code to indicate that a service or procedure has been altered by some specific circumstance but not changed in its definition. Applying the correct modifier is the ultimate test of a coder's compliance knowledge. Incorrect modifier usage is the leading cause of Office of Inspector General (OIG) audits.
CPT codes are intrinsically tied to physician compensation via the Medicare Physician Fee Schedule (MPFS). Every Category I CPT code is assigned a Relative Value Unit (RVU), which quantifies the resources required to perform the service. The total RVU is calculated by adding three components:
The Total RVU is then multiplied by a geographic practice cost index (GPCI) and the annual Medicare Conversion Factor to calculate the exact dollar amount of reimbursement.
The Certified Professional Coder is the final line of defense in the revenue cycle. A physician may perform an incredible, life-saving surgery, but if the CPC fails to correctly sequence the CPT codes, apply the correct NCCI bypass modifiers, or link the procedures to the highest-specificity ICD-10-CM diagnosis codes to prove Medical Necessity, the claim will be denied.
Beyond abstracting codes from documentation, modern CPCs act as clinical educators. They regularly audit provider documentation to ensure compliance with AMA guidelines, train physicians on the nuances of the 2021/2023 E/M updates, and query providers when an operative report lacks the critical details required to assign a complex surgical code.
The CPT code set is a dynamic, continuously evolving language that adapts to the cutting edge of medical science. New technologies, novel surgical techniques, and telemedicine expansions require the AMA to update the manual annually every January 1st.
For the professional medical coder, fluency in CPT is the key to unlocking the financial viability of a healthcare organization. It demands rigorous analytical skills, an unwavering commitment to ethical compliance, and a deep respect for the clinical realities of patient care. Whether you are coding a simple office visit or a multi-stage cardiothoracic surgery, your mastery of CPT ensures that the physician's work is accurately recognized, fully reimbursed, and protected from retrospective audits.
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Looking up medical codes can often be a frustrating and time-consuming experience, especially when relying on slow, clunky platforms or physical manuals that quickly become outdated. Our dedicated CPT search directory elegantly bridges that gap. By utilizing our highly optimized, state-of-the-art database, you can effortlessly find CPT code descriptions by simply typing a keyword, a specific diagnosis or procedure, an anatomical site, or the exact alphanumeric code itself. The results are rendered in real-time as you type, allowing you to completely bypass cumbersome PDF manuals and heavy physical coding books, streamlining your daily workflow.
To perform an accurate CPT lookup, navigate to the intuitive search bar located at the top of this page. If you have a specific clinical term or abstract concept in mind, simply type the term into the search field. Our intelligent, NLP-driven algorithm will instantly scan the entire official database to populate a comprehensive list of matching CPT codes and descriptions. Conversely, if you already possess the specific code and simply need to verify its validity or read the full tabular guidelines, you can type the identifier directly into the bar to instantly verify its official long-form description.
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We highly recommend that you bookmark this page as your daily, primary resource for all your CPT code search needs. We are deeply committed to maintaining this robust, frequently updated database as a permanent, free public utility for the global healthcare data community. Start typing your query into the search bar above to experience the absolute fastest, most reliable medical code lookup available on the internet today. Say goodbye to endless scrolling, frustrating page loads, and outdated indexes. Let our powerful, instantaneous search engine do the heavy lifting for your clinical documentation and coding operations. Whether you are aggressively searching by an exact code, a partial clinical description, or a broad medical category, our advanced tool delivers the exact CPT code information you need to ensure total compliance and financial accuracy.