Search the complete CPT database. Access official guidelines, notes, modifiers, and documentation requirements instantly.
Browse the official clinical code repository for active CPT procedure classifications. Up to 50 codes are displayed per page.
| Code | Category / Specialty | Description |
|---|---|---|
| 81251 |
Procedures
General
|
GBA (glucosidase, beta, acid) (eg, Gaucher disease) gene analysis, common variants (eg, N370S, 84GG, L444P, IVS2+1G>A)
|
| 81252 |
Procedures
General
|
GJB2 (gap junction protein, beta 2, 26kDa, connexin 26) (eg, nonsyndromic hearing loss) gene analysis; full gene sequence
|
| 81253 |
Procedures
General
|
GJB2 (gap junction protein, beta 2, 26kDa, connexin 26) (eg, nonsyndromic hearing loss) gene analysis; known familial variants
|
| 81254 |
Procedures
General
|
GJB6 (gap junction protein, beta 6, 30kDa, connexin 30) (eg, nonsyndromic hearing loss) gene analysis, common variants (eg, 309kb [del(GJB6-D13S1830)] and 232kb [del(GJB6-D13S1854)])
|
| 81255 |
Procedures
General
|
HEXA (hexosaminidase A [alpha polypeptide]) (eg, Tay-Sachs disease) gene analysis, common variants (eg, 1278insTATC, 1421+1G>C, G269S)
|
| 81256 |
Procedures
General
|
HFE (hemochromatosis) (eg, hereditary hemochromatosis) gene analysis, common variants (eg, C282Y, H63D)
|
| 81257 |
Procedures
General
|
HBA1/HBA2 (alpha globin 1 and alpha globin 2) (eg, alpha thalassemia, Hb Bart hydrops fetalis syndrome, HbH disease), gene analysis, for common deletions or variant (eg, Southeast Asian, Thai, Filipino, Mediterranean, alpha3.7, alpha4.2, alpha20.5, and Constant Spring)
|
| 81258 |
Procedures
General
|
HBA1/HBA2 (alpha globin 1 and alpha globin 2) (eg, alpha thalassemia, Hb Bart hydrops fetalis syndrome, HbH disease), gene analysis; known familial variant
|
| 81259 |
Procedures
General
|
HBA1/HBA2 (alpha globin 1 and alpha globin 2) (eg, alpha thalassemia, Hb Bart hydrops fetalis syndrome, HbH disease), gene analysis; full gene sequence
|
| 81260 |
Procedures
General
|
IKBKAP (inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein) (eg, familial dysautonomia) gene analysis, common variants (eg, 2507+6T>C, R696P)
|
| 81261 |
Procedures
General
|
IGH@ (Immunoglobulin heavy chain locus) (eg, leukemias and lymphomas, B-cell), gene rearrangement analysis to detect abnormal clonal population(s); amplified methodology (eg, polymerase chain reaction)
|
| 81262 |
Procedures
General
|
IGH@ (Immunoglobulin heavy chain locus) (eg, leukemias and lymphomas, B-cell), gene rearrangement analysis to detect abnormal clonal population(s); direct probe methodology (eg, Southern blot)
|
| 81263 |
Procedures
General
|
IGH@ (Immunoglobulin heavy chain locus) (eg, leukemia and lymphoma, B-cell), variable region somatic mutation analysis
|
| 81264 |
Procedures
General
|
IGK@ (Immunoglobulin kappa light chain locus) (eg, leukemia and lymphoma, B-cell), gene rearrangement analysis, evaluation to detect abnormal clonal population(s)
|
| 81265 |
Procedures
General
|
Comparative analysis using Short Tandem Repeat (STR) markers; patient and comparative specimen (eg, pre-transplant recipient and donor germline testing, post-transplant non-hematopoietic recipient germline [eg, buccal swab or other germline tissue sample] and donor testing, twin zygosity testing, or maternal cell contamination of fetal cells)
|
| 81266 |
Procedures
General
|
Comparative analysis using Short Tandem Repeat (STR) markers; each additional specimen (eg, additional cord blood donor, additional fetal samples from different cultures, or additional zygosity in multiple birth pregnancies) (List separately in addition to code for primary procedure)
|
| 81267 |
Procedures
General
|
Chimerism (engraftment) analysis, post transplantation specimen (eg, hematopoietic stem cell), includes comparison to previously performed baseline analyses; without cell selection
|
| 81268 |
Procedures
General
|
Chimerism (engraftment) analysis, post transplantation specimen (eg, hematopoietic stem cell), includes comparison to previously performed baseline analyses; with cell selection (eg, CD3, CD33), each cell type
|
| 81269 |
Procedures
General
|
HBA1/HBA2 (alpha globin 1 and alpha globin 2) (eg, alpha thalassemia, Hb Bart hydrops fetalis syndrome, HbH disease), gene analysis; duplication/deletion variants
|
| 81270 |
Procedures
General
|
JAK2 (Janus kinase 2) (eg, myeloproliferative disorder) gene analysis, p.Val617Phe (V617F) variant
|
| 81271 |
Procedures
General
|
HTT (huntingtin) (eg, Huntington disease) gene analysis; evaluation to detect abnormal (eg, expanded) alleles
|
| 81272 |
Procedures
General
|
KIT (v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog) (eg, gastrointestinal stromal tumor [GIST], acute myeloid leukemia, melanoma), gene analysis, targeted sequence analysis (eg, exons 8, 11, 13, 17, 18)
|
| 81273 |
Procedures
General
|
KIT (v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog) (eg, mastocytosis), gene analysis, D816 variant(s)
|
| 81274 |
Procedures
General
|
HTT (huntingtin) (eg, Huntington disease) gene analysis; characterization of alleles (eg, expanded size)
|
| 81275 |
Procedures
General
|
KRAS (v-Ki-ras2 Kirsten rat sarcoma viral oncogene) (eg, carcinoma) gene analysis, variants in codons 12 and 13
|
| 81276 |
Procedures
General
|
KRAS (Kirsten rat sarcoma viral oncogene homolog) (eg, carcinoma) gene analysis; additional variant(s) (eg, codon 61, codon 146)
|
| 81277 |
Procedures
General
|
Cytogenomic neoplasia (genome0wide) microarray analysis; interrogation of genomic regions for copy number and loss-of-heterozygosity variants for chromosomal abnormalities
|
| 81280 |
Procedures
General
|
Long QT syndrome gene analyses (eg, KCNQ1, KCNH2, SCN5A, KCNE1, KCNE2, KCNJ2, CACNA1C, CAV3, SCN4B, AKAP, SNTA1, and ANK2); full sequence analysis
|
| 81281 |
Procedures
General
|
Long QT syndrome gene analyses (eg, KCNQ1, KCNH2, SCN5A, KCNE1, KCNE2, KCNJ2, CACNA1C, CAV3, SCN4B, AKAP, SNTA1, and ANK2); known familial sequence variant
|
| 81282 |
Procedures
General
|
Long QT syndrome gene analyses (eg, KCNQ1, KCNH2, SCN5A, KCNE1, KCNE2, KCNJ2, CACNA1C, CAV3, SCN4B, AKAP, SNTA1, and ANK2); duplication/deletion variants
|
| 81283 |
Procedures
General
|
IFNL3 (interferon, lambda 3) (eg, drug response), gene analysis, rs12979860 variant
|
| 81284 |
Procedures
General
|
FXN (frataxin) (eg, Friedreich ataxia) gene analysis; evaluation to detect abnormal (expanded) alleles
|
| 81285 |
Procedures
General
|
FXN (frataxin) (eg, Friedreich ataxia) gene analysis; characterization of alleles (eg, expanded size
|
| 81286 |
Procedures
General
|
FXN (frataxin) (eg, Friedreich ataxia) gene analysis; full gene sequence
|
| 81287 |
Procedures
General
|
MGMT (O-6-methylguanine-DNA methyltransferase) (eg, glioblastoma multiforme), methylation analysis
|
| 81288 |
Procedures
General
|
MLH1 (mutL homolog 1, colon cancer, nonpolyposis type 2) (eg, hereditary non-polyposis colorectal cancer, Lynch syndrome) gene analysis; promoter methylation analysis
|
| 81289 |
Procedures
General
|
FXN (frataxin) (eg, Friedreich ataxia) gene analysis; known familial variant(s)
|
| 81290 |
Procedures
General
|
MCOLN1 (mucolipin 1) (eg, Mucolipidosis, type IV) gene analysis, common variants (eg, IVS3-2A>G, del6.4kb)
|
| 81291 |
Procedures
General
|
MTHFR (5,10-methylenetetrahydrofolate reductase) (eg, hereditary hypercoagulability) gene analysis, common variants (eg, 677T, 1298C)
|
| 81292 |
Procedures
General
|
MLH1 (mutL homolog 1, colon cancer, nonpolyposis type 2) (eg, hereditary non-polyposis colorectal cancer, Lynch syndrome) gene analysis; full sequence analysis
|
| 81293 |
Procedures
General
|
MLH1 (mutL homolog 1, colon cancer, nonpolyposis type 2) (eg, hereditary non-polyposis colorectal cancer, Lynch syndrome) gene analysis; known familial variants
|
| 81294 |
Procedures
General
|
MLH1 (mutL homolog 1, colon cancer, nonpolyposis type 2) (eg, hereditary non-polyposis colorectal cancer, Lynch syndrome) gene analysis; duplication/deletion variants
|
| 81295 |
Procedures
General
|
MSH2 (mutS homolog 2, colon cancer, nonpolyposis type 1) (eg, hereditary non-polyposis colorectal cancer, Lynch syndrome) gene analysis; full sequence analysis
|
| 81296 |
Procedures
General
|
MSH2 (mutS homolog 2, colon cancer, nonpolyposis type 1) (eg, hereditary non-polyposis colorectal cancer, Lynch syndrome) gene analysis; known familial variants
|
| 81297 |
Procedures
General
|
MSH2 (mutS homolog 2, colon cancer, nonpolyposis type 1) (eg, hereditary non-polyposis colorectal cancer, Lynch syndrome) gene analysis; duplication/deletion variants
|
| 81298 |
Procedures
General
|
MSH6 (mutS homolog 6 [E. coli]) (eg, hereditary non-polyposis colorectal cancer, Lynch syndrome) gene analysis; full sequence analysis
|
| 81299 |
Procedures
General
|
MSH6 (mutS homolog 6 [E. coli]) (eg, hereditary non-polyposis colorectal cancer, Lynch syndrome) gene analysis; known familial variants
|
| 81300 |
Procedures
General
|
MSH6 (mutS homolog 6 [E. coli]) (eg, hereditary non-polyposis colorectal cancer, Lynch syndrome) gene analysis; duplication/deletion variants
|
| 81301 |
Procedures
General
|
Microsatellite instability analysis (eg, hereditary non-polyposis colorectal cancer, Lynch syndrome) of markers for mismatch repair deficiency (eg, BAT25, BAT26), includes comparison of neoplastic and normal tissue, if performed
|
| 81302 |
Procedures
General
|
MECP2 (methyl CpG binding protein 2) (eg, Rett syndrome) gene analysis; full sequence analysis
|
The Current Procedural Terminology (CPT®) code set, maintained and copyrighted by the American Medical Association (AMA), is the universal language of medicine in the United States outpatient setting. It is utilized to report medical, surgical, and diagnostic procedures and services to entities such as physicians, health insurance companies, and accreditation organizations. For the Certified Professional Coder (CPC), mastering the CPT manual is the cornerstone of professional fee (ProFee) and ambulatory surgery center (ASC) coding.
Unlike ICD-10-CM which describes the "why" (the diagnosis), CPT describes the "what" (the service or procedure performed). Translating a complex operative report or an Evaluation and Management (E/M) encounter into a 5-digit CPT code requires a profound understanding of medical terminology, anatomy, and the labyrinth of AMA guidelines. A single coding error can result in massive revenue leakage, compliance violations, or severe audit penalties.
Never code directly from the alphabetic index. The true power of the CPC lies in reading the parenthetical notes situated directly beneath the CPT codes in the tabular section. These notes dictate bundling rules, direct the coder to the correct alternative codes, and provide strict instructions on when a modifier is necessary. Ignoring a parenthetical note is a guaranteed path to a claim denial.
The CPT code set is divided into three distinct categories, each serving a unique purpose in the healthcare ecosystem.
These are the core, 5-digit numeric codes that make up the vast majority of the CPT manual. They represent procedures and services that are widely performed by many healthcare professionals in clinical practice and are approved by the FDA. Category I is divided into six main sections:
These are supplemental tracking codes used for performance measurement and quality tracking. They are alphanumeric (e.g., 3008F - Body Mass Index documented). While Category II codes are generally optional and do not carry a relative value unit (RVU) for direct reimbursement, they are highly critical in value-based purchasing agreements, MIPS (Merit-based Incentive Payment System), and MACRA reporting to secure quality bonuses.
These are temporary alphanumeric codes (ending in "T") utilized for emerging technologies, services, and procedures (e.g., 0101T - Extracorporeal shock wave involving musculoskeletal system). They allow researchers and the AMA to track the utilization of new technologies before they are granted Category I status. If a Category III code exists for a specific procedure, it must be utilized instead of an "unlisted" Category I code.
Historically, E/M coding was the most heavily audited and contentious area of medical coding, governed by the archaic 1995 and 1997 CMS Documentation Guidelines. These old guidelines required physicians to "bullet count" physical exam elements and history of present illness (HPI) components, leading to massive documentation bloat ("note bloat") in Electronic Health Records.
The AMA and CMS radically overhauled E/M coding (effective 2021 for outpatient/office, and 2023 for inpatient/facility). Today, the selection of an E/M level is based strictly on one of two criteria:
Surgical coding is governed by the concept of the Global Surgical Package. When a payer reimburses a surgical CPT code, the payment covers not just the intraoperative procedure, but also the local/topical anesthesia, normal uncomplicated follow-up care, and typical preoperative encounters.
One of the primary directives of a CPC is to prevent Unbundling. Unbundling occurs when a coder reports multiple CPT codes for components that are inherently part of a single, major procedure. To prevent this, coders rely on the National Correct Coding Initiative (NCCI) Edits. These edits dictate which codes cannot be billed together. For example, you cannot bill an exploratory laparotomy alongside an open appendectomy, as the surgical approach is bundled into the definitive procedure.
Modifiers are two-digit codes appended to a CPT code to indicate that a service or procedure has been altered by some specific circumstance but not changed in its definition. Applying the correct modifier is the ultimate test of a coder's compliance knowledge. Incorrect modifier usage is the leading cause of Office of Inspector General (OIG) audits.
CPT codes are intrinsically tied to physician compensation via the Medicare Physician Fee Schedule (MPFS). Every Category I CPT code is assigned a Relative Value Unit (RVU), which quantifies the resources required to perform the service. The total RVU is calculated by adding three components:
The Total RVU is then multiplied by a geographic practice cost index (GPCI) and the annual Medicare Conversion Factor to calculate the exact dollar amount of reimbursement.
The Certified Professional Coder is the final line of defense in the revenue cycle. A physician may perform an incredible, life-saving surgery, but if the CPC fails to correctly sequence the CPT codes, apply the correct NCCI bypass modifiers, or link the procedures to the highest-specificity ICD-10-CM diagnosis codes to prove Medical Necessity, the claim will be denied.
Beyond abstracting codes from documentation, modern CPCs act as clinical educators. They regularly audit provider documentation to ensure compliance with AMA guidelines, train physicians on the nuances of the 2021/2023 E/M updates, and query providers when an operative report lacks the critical details required to assign a complex surgical code.
The CPT code set is a dynamic, continuously evolving language that adapts to the cutting edge of medical science. New technologies, novel surgical techniques, and telemedicine expansions require the AMA to update the manual annually every January 1st.
For the professional medical coder, fluency in CPT is the key to unlocking the financial viability of a healthcare organization. It demands rigorous analytical skills, an unwavering commitment to ethical compliance, and a deep respect for the clinical realities of patient care. Whether you are coding a simple office visit or a multi-stage cardiothoracic surgery, your mastery of CPT ensures that the physician's work is accurately recognized, fully reimbursed, and protected from retrospective audits.
Welcome to the most comprehensive and lightning-fast CPT code lookup tool available online. Whether you are a dedicated health information management (HIM) professional, a certified medical coder, a specialized biller, or a clinical data analyst, our advanced search engine allows you to instantly search CPT codes and find highly accurate code descriptions in mere milliseconds. Navigating the complex world of healthcare terminology requires precision, and our platform is built to deliver exactly that.
Looking up medical codes can often be a frustrating and time-consuming experience, especially when relying on slow, clunky platforms or physical manuals that quickly become outdated. Our dedicated CPT search directory elegantly bridges that gap. By utilizing our highly optimized, state-of-the-art database, you can effortlessly find CPT code descriptions by simply typing a keyword, a specific diagnosis or procedure, an anatomical site, or the exact alphanumeric code itself. The results are rendered in real-time as you type, allowing you to completely bypass cumbersome PDF manuals and heavy physical coding books, streamlining your daily workflow.
To perform an accurate CPT lookup, navigate to the intuitive search bar located at the top of this page. If you have a specific clinical term or abstract concept in mind, simply type the term into the search field. Our intelligent, NLP-driven algorithm will instantly scan the entire official database to populate a comprehensive list of matching CPT codes and descriptions. Conversely, if you already possess the specific code and simply need to verify its validity or read the full tabular guidelines, you can type the identifier directly into the bar to instantly verify its official long-form description.
Our platform is meticulously engineered specifically for medical coders, billers, and clinical analysts who demand both speed and unwavering accuracy. When you search for CPT codes on our website, you are guaranteed to receive the exact, official nomenclature published by the governing bodies. We provide the full tabular descriptions, ensuring that you understand the precise clinical nuances, including essential modifiers, bundling edits, and specific indicators required for clean claim submission and flawless clinical documentation.
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We highly recommend that you bookmark this page as your daily, primary resource for all your CPT code search needs. We are deeply committed to maintaining this robust, frequently updated database as a permanent, free public utility for the global healthcare data community. Start typing your query into the search bar above to experience the absolute fastest, most reliable medical code lookup available on the internet today. Say goodbye to endless scrolling, frustrating page loads, and outdated indexes. Let our powerful, instantaneous search engine do the heavy lifting for your clinical documentation and coding operations. Whether you are aggressively searching by an exact code, a partial clinical description, or a broad medical category, our advanced tool delivers the exact CPT code information you need to ensure total compliance and financial accuracy.